Viridian City is a small, beautiful city located in western Kantō, enveloped in green year-round. The Ground-type Gym is located here.

Pewter City is a city located in northwest Kantō. The locale lies between Viridian Forest (via Route 2) and Mt. Moon (via Route 3). It's a quiet city nestled between rugged mountains and rocks, and home to the Rock-type Pokémon Gym.

Mt. Moon is a mountain located in northern Kantō, between Pewter City in the west and Cerulean City in the east. It is known for being one of the few places where wild Clefairy can be found, and for its frequent meteor falls. The shards of meteorites that fall here become Moon Stones, which is where the mountain got its name. The mountain is also known for being home to several Pokémon Fossils.

Cerulean City is a beautiful seaside city located in northern Kantō. It is situated near a sea inlet to the north, with Saffron City to the south, and Mt. Moon to the west.

Cerulean is a mid-sized city with a few attractions, including the Bike Shop and the Berry Powder man.

Diglett's Cave is a long tunnel dug by wild Diglett and Dugtrio in Kantō. The northern entrance is on Route 2, south of Pewter City, and the southern entrance is on Route 11, near the eastern edge of Vermilion City

Situated near a sea inlet to the south, Vermillion City serves as a popular sea port for ships such as the S.S. Anne. Vermilion Harbor is a home port for many ships:
The S.S. Anne sails around the world and returns to Vermilion once a year.
The S.S. Aqua sails from Olivine City in Johto to Vermilion Harbor.
The Seagallop Ferries sail regularly to all of the Sevii Islands.

Aside from the harbor, the other exits to the city are Route 11 and Diglett's Cave to the east. North of the city is Route 6.

Lavender Town is a small town located in northeast Kantō, just south of the Rock Tunnel. In recent years, the town has become noticeably modernized with the inclusion of a broadcasting station taking up the place of the old Pokémon Tower. The frustrated citizens claim the ghosts that appear in the Tower are the spirits of Pokémon that have died.

North of Lavender is Route 10 and the Rock Tunnel. West of the town is Route 8, while to the south is Route 12 and the Silence Bridge.

Celadon City is located in central Kantō. It is the most populous city in Kantō and the eighth most populous in the Pokémon world, surpassing even Saffron City in the east. The city has two entrances, one from the east via Route 7, and one from the west via Route 16.

Celadon is the main place to spend money in Kantō, through the Celadon Department Store and the Celadon Game Corner. It is the home of the Celadon Condominiums, where residents of the city live, and the Celadon Hotel, where visitors can rest. Celadon is also home to the Grass-type Gym.

Fuchsia City is a city located in southwest Kantō. Its most distinguishing features are the Pal Park and the Poison-type Gym. It's
a historic village that has become new.

Saffron City is a sprawling metropolis in the Kantō region. It lies in between Celadon City, Vermilion City, Lavender Town, and Cerulean City.

It is the largest and one of the busiest cities in Kantō, being famous even in other regions. It is the tenth most populous city in the Pokémon world. The large Silph Co. headquarters building stands firm as the city's centerpiece while the Pyschic Gym and Fighting Dojo dominate the north-eastern corner district. Not only is this the central business district of Kantō, it also holds the region's largest infrastructure, including the Magnet Train station, which allows ease of access between Kantō and Johto.

Cinnabar Island is a large island located off the southern coast of the Kantō region, south of Pallet Town. It is home to a large volcano.

Cinnabar Island is a technological mecca. The journals scattered about the abandoned Pokémon Mansion suggest that Mewtwo was cloned here, reflected by the fact that the scientists at the Pokémon Lab have the ability to resurrect Pokémon from their Fossils.

Blaine was once the resident Gym Leader specializing in Fire-type Pokémon, but a volcano erupted on the island, destroying everything. The Pokémon Center was rebuilt, and the Cinnabar Gym has been relocated to the Seafoam Islands.

Cinnabar is a kind of red mineral, associated with hot springs and volcanoes. The island is connected to the mainland by two water routes: Route 20 in the east and Route 21 in the north, leading to Fuchsia City and Pallet Town, respectively.